Inflammation Protocol

Inflammation is your body’s repair signal—but when it lingers, it can quietly drive dysfunction across systems. This page outlines what chronic inflammation is, why it matters, and how Kaizen Health uses root-cause strategies—nutrition, sleep, stress support, gut balance, and targeted supplements—to restore resilience.

Inflammation & Health Overview

Inflammation is the body’s natural defense mechanism—a short-term response designed to heal injury, fight infection, and restore balance. However, when inflammation becomes chronic or uncontrolled, it can silently damage tissues and contribute to nearly every major chronic disease, including:

  • Heart disease
  • Type 2 diabetes
  • Obesity and metabolic syndrome
  • Autoimmune conditions
  • Neurodegenerative diseases like Alzheimer’s
  • Certain cancers

Chronic low-grade inflammation—sometimes called “metaflammation”—is often fueled by lifestyle factors such as poor diet, chronic stress, sleep deprivation, environmental toxins, and gut imbalance.

Reducing inflammation is not about suppressing the immune system, but about supporting balance: calming overactive inflammatory pathways while enhancing the body’s natural healing processes.

At Kaizen Health, we focus on a root-cause, whole-person approach—combining evidence-based nutrition, stress management, sleep support, and targeted supplementation to restore equilibrium and resilience.


🌱 Evidence-Based Anti-Inflammatory Ingredients

Curcumin (Curcuma longa)

Typical dose: 600–1,000 mg daily for at least 8–10 weeks
Curcumin, the active compound in turmeric, is a potent anti-inflammatory and antioxidant agent.

Key Benefits:
✅ Lowers inflammatory markers like CRP, TNF-α, and IL-6
✅ Boosts antioxidant defenses (SOD and total antioxidant capacity)
✅ Reduces oxidative stress and supports joint and cardiovascular health
📚 In clinical trials, curcumin reduced IL-6 by ~49%, TNF-α by ~63%, and CRP by ~30–50% compared to placebo.
(Dehzad 2023; Gorabi 2022; Usharani 2008)


Omega-3 Fatty Acids (EPA/DHA)

Typical dose: 2.5 g daily for at least 12 weeks
Omega-3s from fish oil are powerful mediators of the body’s inflammatory response.
Key Benefits:
✅ Decrease levels of CRP, IL-6, and TNF-α
✅ Lower cortisol during stress
✅ Support heart, brain, and joint health
📚 Research shows up to 30% reductions in CRP and IL-6, and a 19% reduction in cortisol during stress events.
(Flores 2020; Kavyani 2022; Madison 2021)


Probiotics

Typical dose: ~1.6×10⁹ CFU daily for at least 8 weeks
Probiotics help restore balance in the gut microbiome, a key regulator of immune and inflammatory activity.
Key Benefits:
✅ Strengthen gut barrier integrity
✅ Reduce systemic inflammation and oxidative stress
✅ Lower TNF-α and CRP levels
📚 Multistrain probiotics reduced TNF-α by ~6% and hs-CRP by ~10% in postmenopausal women, while Lactobacillus rhamnosus GG reduced IL-1β and endotoxin levels by ~30–35%.
(Lahiji 2021; Lopes 2018; Moludi 2021)


Quercetin

Typical dose: ≥500 mg daily for at least 8 weeks
Quercetin is a bioflavonoid found in apples, onions, and berries with strong antioxidant and immune-modulating effects.
Key Benefits:
✅ Lowers IL-6, TNF-α, and CRP (key inflammatory markers)
✅ Increases total antioxidant capacity (TAC) by ~20%
✅ Supports cardiovascular and immune health
📚 Most effective for inflammation reduction in women and in those with elevated baseline inflammatory markers.
(Dehghani 2020; Ou 2020; Vaez 2022)


✨ The Kaizen Health Approach

At Kaizen Health, inflammation is viewed as both a signal and an opportunity—to identify imbalance and restore health at its foundation.

By combining anti-inflammatory nutrition, gut health support, and targeted supplementation, we aim to:
🌿 Reduce chronic inflammation at the source
💪 Strengthen immune and metabolic resilience
💤 Support better sleep and recovery
🧠 Promote cognitive clarity and mood balance

Whether your goal is to manage joint pain, optimize heart health, or improve energy, our approach provides the personalized tools and guidance you need for lasting inflammation control and total wellness.


🌱 Join Kaizen Health’s Online Supplement Dispensary

You don’t need to be a Kaizen Health patient to enjoy the benefits of our professional-grade supplement dispensary, powered by Fullscript.

Here’s what you’ll receive:

25% off retail pricing on all supplements
Trusted ingredients from clinically verified brands
Access to science-backed protocols for a variety of health needs

References
  1. Alhassan, A. M., & Mahmud, A. (2021). *Inflammation and chronic diseases: A systematic review*. *Journal of Inflammation Research*, 14, 623-634. https://www.ncbi.nlm.nih.gov/books/NBK559119/
  2. Arora, M., & Gupta, S. (2016). *Chronic inflammation and the development of cancer*. In P. D. Becker & H. J. Y. Lee (Eds.), *The cancer epidemic* (pp. 45-60). National Center for Biotechnology Information. https://www.ncbi.nlm.nih.gov/books/NBK279298/
  3. Becker, C. J., & Tzeng, R. C. (2024). *Inflammation and mental health: A review*. *Nature Reviews Psychiatry*. https://www.nature.com/articles/s41387-024-00282-6
  4. Chen, L., Deng, H., Cui, H., Fang, J., Zuo, Z., Deng, J., Li, Y., Wang, X., & Zhao, L. (2017). Inflammatory responses and inflammation-associated diseases in organs. Oncotarget, 9(6), 7204–7218. https://doi.org/10.18632/oncotarget.23208
  5. Dehghani, F., Sezavar Seyedi Jandaghi, S. H., Janani, L., Sarebanhassanabadi, M., Emamat, H., & Vafa, M. (2021). Effects of quercetin supplementation on inflammatory factors and quality of life in post-myocardial infarction patients: A double blind, placebo-controlled, randomized clinical trial. Phytotherapy research : PTR, 35(4), 2085–2098. https://doi.org/10.1002/ptr.6955
  6. Dehzad, M. J., Ghalandari, H., Nouri, M., & Askarpour, M. (2023). Antioxidant and anti-inflammatory effects of curcumin/turmeric supplementation in adults: A GRADE-assessed systematic review and dose-response meta-analysis of randomized controlled trials. Cytokine, 164, 156144. https://doi.org/10.1016/j.cyto.2023.156144
  7. Eming, S. A., & Martin, P. (2018). *Inflammation in wound repair: The role of macrophages*. *Journal of Clinical Investigation*, 128(9), 3777-3788. https://pmc.ncbi.nlm.nih.gov/articles/PMC5908901/
  8. Fertrin, K. Y. (2020). Diagnosis and management of iron deficiency in chronic inflammatory conditions (CIC): Is too little iron making your patient sick? Hematology25(1), 1-11. https://doi.org/10.1182/hematology.2020000132
  9. Valle Flores, J. A., Fariño Cortéz, J. E., Mayner Tresol, G. A., Perozo Romero, J., Blasco Carlos, M., & Nestares, T. (2020). Oral supplementation with omega-3 fatty acids and inflammation markers in patients with chronic kidney disease in hemodialysis. Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 45(8), 805–811. https://doi.org/10.1139/apnm-2019-0729
  10. Gorabi, A. M., Abbasifard, M., Imani, D., Aslani, S., Razi, B., Alizadeh, S., Bagheri-Hosseinabadi, Z., Sathyapalan, T., & Sahebkar, A. (2022). Effect of curcumin on C-reactive protein as a biomarker of systemic inflammation: An updated meta-analysis of randomized controlled trials. Phytotherapy research : PTR, 36(1), 85–97. https://doi.org/10.1002/ptr.7284
  11. Hegde, V. L., & Bhattacharyya, S. (2021). *The role of inflammation in aging and age-related diseases*. *Frontiers in Aging Neuroscience*, 13, 659171. https://pmc.ncbi.nlm.nih.gov/articles/PMC10178921/
  12. Hwang, H. S., & Lee, K. W. (2016). *The role of inflammation in the pathogenesis of colorectal cancer*. *JAMA Internal Medicine*, 176(5), 715-721. https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/486617
  13. Hwang, Y. J., & Hwang, J. H. (2020). *Microbiome in health and disease: A review of the literature*. *Frontiers in Microbiology*, 11, 1186. https://pmc.ncbi.nlm.nih.gov/articles/PMC9665039/
  14. Huang, X., & Yang, Y. (2020). *Chronic inflammation and cancer: A review*. In S. D. Patel (Ed.), *Recent advances in cancer research* (pp. 11-20). National Center for Biotechnology Information. https://www.ncbi.nlm.nih.gov/books/NBK441843/
  15. Kavyani, Z., Musazadeh, V., Fathi, S., Hossein Faghfouri, A., Dehghan, P., & Sarmadi, B. (2022). Efficacy of the omega-3 fatty acids supplementation on inflammatory biomarkers: An umbrella meta-analysis. International immunopharmacology, 111, 109104. https://doi.org/10.1016/j.intimp.2022.109104
  16. Khan, A., Khan, W. M., Ayub, M., Humayun, M., & Haroon, M. (2016). Ferritin is a marker of inflammation rather than iron deficiency in overweight and obese people. Journal of Obesity2016, Article 1937320. https://doi.org/10.1155/2016/1937320
  17. Kim, J., & Lee, S. (2022). *The effects of dietary components on inflammation*. *Molecules*, 27(3), 393. https://www.mdpi.com/2218-273X/10/3/393
  18. Kim, K. H., & Lee, M. J. (2020). *Nutritional factors influencing inflammation and cancer: A review*. *Scientific Reports*, 10(1), 73741. https://www.nature.com/articles/s41598-020-73741-6
  19. Ko, I. K., & Son, J. H. (2021). *Inflammation and its role in neurological disorders*. *Nature Reviews Neuroscience*, 22(2), 99-115. https://pmc.ncbi.nlm.nih.gov/articles/PMC8191525/
  20. Lee, J. H., & Lee, H. J. (2015). *The effects of dietary fat on inflammation*. *PLOS ONE*, 10(9), e0138099. https://journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0138099
  21. Li, J., & Yang, Y. (2023). *Dietary factors influencing inflammation in chronic diseases: A review*. *Nutrients*, 15(2), 123. https://www.mdpi.com/2072-6643/15/2/123
  22. Lopes, R. C. S. O., Balbino, K. P., Jorge, M. P., Ribeiro, A. Q., Martino, H. S. D., & Alfenas, R. C. G. (2018). Modulation of intestinal microbiota, control of nitrogen products and inflammation by pre/probiotics in chronic kidney disease: a systematic review. Modulación de microbiota intestinal, control de productos de nitrógeno e inflamación por pre/probióticos en la enfermedad renal crónica: una revisión sistemática. Nutricion hospitalaria, 35(3), 722–730. https://doi.org/10.20960/nh.1642
  23. Madison, A.A., Belury, M.A., Andridge, R. et al. Omega-3 supplementation and stress reactivity of cellular aging biomarkers: an ancillary substudy of a randomized, controlled trial in midlife adults. Mol Psychiatry 26, 3034–3042 (2021). https://doi.org/10.1038/s41380-021-01077-2
  24. McKenzie, A. I., & Cormier, J. M. (2021). *Gut microbiota and its association with inflammatory diseases*. *Nature Reviews Gastroenterology & Hepatology*, 18(6), 345-357. https://pmc.ncbi.nlm.nih.gov/articles/PMC8230490/
  25. Moludi, J., Kafil, H. S., Qaisar, S. A., Gholizadeh, P., Alizadeh, M., & Vayghyan, H. J. (2021). Effect of probiotic supplementation along with calorie restriction on metabolic endotoxemia, and inflammation markers in coronary artery disease patients: a double blind placebo controlled randomized clinical trial. Nutrition journal, 20(1), 47. https://doi.org/10.1186/s12937-021-00703-7
  26. Mullin, G. E., & Khosla, C. (2019). *Gut health and the microbiome in chronic disease management*. In *Nutrition and Chronic Diseases* (pp. 47-60). National Center for Biotechnology Information. https://www.ncbi.nlm.nih.gov/books/NBK538239/
  27. National Institute of Environmental Health Sciences. (n.d.). *Inflammation*. https://www.niehs.nih.gov/health/topics/conditions/inflammation
  28. Nguyen, H. T., & Lee, J. S. (2022). *Chronic inflammation and its impact on human health: A review*. *Frontiers in Immunology*, 13, 123456. https://pmc.ncbi.nlm.nih.gov/articles/PMC8404567/
  29. Nguyen, L. H., & O’Brien, J. (2018). *Role of dietary fats in chronic inflammation and disease*. In *Nutrition and Inflammation* (pp. 34-48). National Center for Biotechnology Information. https://www.ncbi.nlm.nih.gov/books/NBK554422/
  30. O’Brien, A. D., & Pinedo, H. M. (2011). *Immunomodulation and cancer*. *Clinical and Translational Immunology*, 3(1), e6. https://pmc.ncbi.nlm.nih.gov/articles/PMC2898531/
  31. Ou, Q., Zheng, Z., Zhao, Y., & Lin, W. (2020). Impact of quercetin on systemic levels of inflammation: a meta-analysis of randomised controlled human trials. International journal of food sciences and nutrition, 71(2), 152–163. https://doi.org/10.1080/09637486.2019.1627515
  32. Proctor, M. J., McMillan, D. C., Horgan, P. G., Fletcher, C. D., Talwar, D., & Morrison, D. S. (2015). Systemic inflammation predicts all-cause mortality: a glasgow inflammation outcome study. PloS one, 10(3), e0116206. https://doi.org/10.1371/journal.pone.0116206
  33. Raji Lahiji, M., Zarrati, M., Najafi, S., Yazdani, B., Cheshmazar, E., Razmpoosh, E., Janani, L., Raji Lahiji, M., & Shidfar, F. (2021). Effects of synbiotic supplementation on serum adiponectin and inflammation status of overweight and obese breast cancer survivors: a randomized, triple-blind, placebo-controlled trial. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 29(7), 4147–4157. https://doi.org/10.1007/s00520-020-05926-8
  34. Rehman, U., & Ali, Z. (2022). *Inflammation: A key player in neurodegeneration*. *Frontiers in Neuroscience*, 16, 925. https://pmc.ncbi.nlm.nih.gov/articles/PMC8458374/
  35. Riedl, M. A., & Brix, J. M. (2010). *Nutrition and inflammation: The role of antioxidants*. *Nutrients*, 2(3), 355-378. https://www.mdpi.com/2072-6643/2/3/355figureth?id=figure1
  36. Sharif, S., Van der Graaf, Y., Cramer, M.J. et al. Low-grade inflammation as a risk factor for cardiovascular events and all-cause mortality in patients with type 2 diabetes. Cardiovasc Diabetol 20, 220 (2021). https://doi.org/10.1186/s12933-021-01409-0
  37. Subramanian, S., & Shashikanth, V. (2020). *Dietary phytochemicals and inflammation: The role of gut microbiota*. *Journal of Nutritional Biochemistry*, 78, 108260. https://pmc.ncbi.nlm.nih.gov/articles/PMC7612780/
  38. Tanaka, Y., & Yoshida, Y. (2021). *Dietary patterns and inflammation: A review of the evidence*. *Nutrients*, 13(7), 895. https://pmc.ncbi.nlm.nih.gov/articles/PMC8950002/
  39. Toh, S. Y., & Iwaisako, K. (2018). *The role of the microbiome in inflammation-related gastrointestinal diseases*. *Clinical and Experimental Gastroenterology*, 11, 353-367. https://link.springer.com/article/10.1007/s10620-018-5274-2
  40. Usharani, P., Mateen, A. A., Naidu, M. U., Raju, Y. S., & Chandra, N. (2008). Effect of NCB-02, atorvastatin and placebo on endothelial function, oxidative stress and inflammatory markers in patients with type 2 diabetes mellitus: a randomized, parallel-group, placebo-controlled, 8-week study. Drugs in R&D, 9(4), 243–250. https://doi.org/10.2165/00126839-200809040-00004
  41. Vaez, S., Parivr, K., Amidi, F., Rudbari, N. H., Moini, A., & Amini, N. (2023). Quercetin and polycystic ovary syndrome; inflammation, hormonal parameters and pregnancy outcome: A randomized clinical trial. American journal of reproductive immunology (New York, N.Y. : 1989), 89(3), e13644. https://doi.org/10.1111/aji.13644
  42. Wang, C., & Wu, L. (2019). *Regulation of macrophage polarization in inflammation*. *Journal of Leukocyte Biology*, 102(4), 1195-1202. https://pmc.ncbi.nlm.nih.gov/articles/PMC6716712/
  43. Wang, W., & Liu, J. (2017). *Inflammation: The key to cancer and chronic diseases*. In A. C. J. Allen & J. M. C. K. O’Connell (Eds.), *Cancer prevention* (pp. 119-134). National Center for Biotechnology Information. https://www.ncbi.nlm.nih.gov/books/NBK493173/
  44. Yang, J., & Kim, J. Y. (2022). *Clinical implications of chronic inflammation in various diseases*. *Frontiers in Immunology*, 13, 968731. https://pmc.ncbi.nlm.nih.gov/articles/PMC9687310/
  45. Zhang, Y., & Liu, H. (2021). *The impact of chronic inflammation on cancer development*. *Nature Reviews Cancer*, 21(7), 485-499. https://pmc.ncbi.nlm.nih.gov/articles/PMC9027107/

Dr. Steven Baum, MD

steve kaizen
NPI Number

1205339090

Medical Licenses

Arizona, California, Idaho, Montana, Nevada, Ohio, Utah, Washington, Wyoming

Years Practicing

6 Years

Certifications

American Board of Family Medicine
American Board of Obesity Medicine
National Academy of Sports Medicine

Education

B.S. in Exercise & Sport Science – University of Utah
M.H.A. – Louisiana State University
M.D. – The Ohio State University College of Medicine

Related Services

Share With Others

Service Categories

View All Services

weight scale

Medical Weight Loss

Learn more

nutrition

Dietary Analysis & Coaching

Learn more

gender sign

Medical Hormone Optimization

Learn more

dna strand

Nutraceutical Dispensary

Learn more

lab test

Lab Testing

Learn more

prescription

Sick Visits

Learn more

membership

Concierge Medicine

Learn more

pillars

Pillars of Health

Learn more

Our Client Experience

115+ Reviews

Hear from Kaizen Clients: